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Deborah K. Hanula has a year of Journalism training from Humber College, a Political Science degree from the University of Waterloo, and a Law degree from the University of British Columbia. In addition, she has Diplomas in Cognitive Behavioural Therapy, Child Psychology, and Psychotherapy and Counselling as well as a Family Life Educator and Coach Certificate and Certificates in Reflexology, Assertiveness Training, and Mindfulness Meditation. She is the author of five cookbooks, primarily concerned with gluten-free and dairy-free diets, although one pertains to chocolate. As an adult, in the past she worked primarily as a lawyer, but also as a university and college lecturer, a tutor, editor, writer, counsellor, researcher and piano teacher. She enjoys a multi-faceted approach when it comes to life, work and study, in order to keep things fresh and interesting. Check out her new book: A Murder of Crows & Other Poems (2023).

Monday, November 21, 2011

Endocannabinoid System and THC Mimics

The endocannabinoid system is an elaborate network of receptors and proteins that operate within the brain, heart, gut, liver, and throughout the central nervous system.  The system plays a powerful role in regulating cravings, mood, pain and memory. When bound by cannabinoids, they boost appetite and mood. (1)  THC which is acronym for the active ingredient in marijuana, tetrahydrocannabinol, binds to these receptors.

Three THC knock-offs are gaining popularity on the black market and are commonly found in illicit products marketed as "Spice".  The first mimic is HU-210.  It has a similar chemical composition to THC, but is 100 times more powerful. The second mimic is JWH-073.  It is one of the easiest to  produce.  CP 47,497  is the third.  It is highly potent  and its long-lasting psychological effects make it highly addictive. (2)

D.
(1) and (2), "Tracking the Craving Killer", Discover (November 2011), pp. 12 - 13.

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